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Progress in Medicinal Chemistry : Volume 29 - book by King, F.D.;Lawton, G.;Oxford, A.W.;Ellis, G.P.;Luscombe, D.K.;Ellis, G.P.;Luscombe, D.K.

The book entitled: "Progress in Medicinal Chemistry : Volume 29" is in the Pharmacology Pharmaceutical Science and Toxicology Other Books section of Pharmacology, Pharmaceutical Science and Toxicology Books area...

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DESCRIPTION: The 29th volume of the series presents yet again, an exemplary survey of a wide range of current topics in medicinal chemistry and pharmacology. Eight expert reviews emphasize the relationships between chemical structure and pharmacological activity. These detailed discussions of some of the most exciting developments in the field today, will prove of great value to future research.
The book begins with a study of anti-inflammatory activities of 5-lipoxygenase inhibitors, followed by an overview of the antiarrhythmic therapeutic possibilities offered by Class III electrophysiological agents. Structures and activities of some opioid ligands are surveyed, and the investigation into pharmacologically active pyridazine derivatives is continued. Dopamine D2 receptor agonists offer exciting therapeutic potential, as do ondansetron and related 5-HT3 antagonists. The herbal origin of many modern drugs is yet again reflected in a survey o

TABLE OF CONTENTS: 5-Lipoxygenase Inhibitors and their Anti-inflammatory Activities (D.G. Batt).
An Overview of Class III Electrophysiological Agents: A New Generation of
Antiarrhythmic Therapy (T.K. Morgan, Jr., M.E. Sullivan). Chemical Structures
and Biological Activities of Non-Peptide Selective Kappa Opioid Ligands (D.C.
Rees). Pharmocologically Active Pyridazine Dervatives. Part 2 (G. Heinisch,
H. Kopelent-Frank). Centrally Acting Dopamine D2 Receptor Ligands: Agonists
(H. Wikström). Progress in the Medicinal Chemistry of the Herb Feverfew
(W.A. Groenewegen, D.W. Knight, S. Heptinstall). Ondansetron and Related 5-
HT3 Antagonists: Recent Advances (A.W. Oxford, J.A. Bell, G.J.
Kilpatrick, S.J. Ireland, M.B. Tyers). Synthetic Inhibitors of Bacterial and
Mammalian Interstitial Collagenases (M.A. Schwartz, H.E. van Wart). Index.
Author Index. Subject Index.

AUTHORS: King, F.D.;Lawton, G.;Oxford, A.W.;Ellis, G.P.;Luscombe, D.K.;Ellis, G.P.;Luscombe, D.K.

PAGES: 350 pages

PUBLISH DATE: 01/03/1992

ISBN Number: 0-444-89472-1

USA Book Price: $207
UK Book Price: £138

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