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Genetics of Sex Determination - book by Verma, R.S.
The book entitled: "Genetics of Sex Determination" is in the Genetics Books section of Life Sciences Books area...
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DESCRIPTION: The Genetical Theory of Natural Selection by R.A. Fisher (1930) dictated that sexual dimorphisms may depend upon a single medelian factor. This could be true for some species but his suggestion could not take off the ground as gender in Drosophila is determined by the number of X chromosomes. Technical advances in molecular biology have revived the initial thinking of Fisher and dictate that TDF or SRY genes in humans or Tdy in mice are sex determining genes. The fortuitous findings of XX males and XY female, which are generally termed sex reversal phenomenon, are quite bewildering traits that have caused much amazement concerning the pairing mechanism(s) of the pseudoautosomal regions of human X and Y chromosomes at meiosis. These findings have opened new avenues to explore further the genetic basis of sex determination at the single gene level.
The aim of the fourth volume, titled Genetics of Sex Determination is to reflect on the latest
TABLE OF CONTENTS: Contents. List of Contributors. Preface (R.S. Verma). Genetics of Sex Determination: An Overview (R. Mittwoch). The Testis Determining Gene, SRY (M. O'Neill and A. Sinclair). Sex Reversal in Mammals (C.M. Nagamine). Molecular Genetics of X-Chromosome Inactivation (M.F. Lyon). Sex Chromosome Aberrations and Genetic Consequences (H. Anhalt and E.K. Neely). Genetics of Male Pseudohermaphroditism and True Hermaphroditism (J.L. Simpson). Pseudoautosomal Regions at the Tip of the Short and long Arms of the Human Sex Chromosomes (G.A. Rappold). Temperature Dependent Sex Determination: Evaluation and Hypothesis (A.M. Coriat and P.T. Sharpe). Mammalian Spermatogenesis (D.W. Hale). Mechanism of Sex Determination in Mammals (K. McElreavey). Commentary: Genes, Chromosomes, and Sex (R.S. Verma). Index.
AUTHORS: Verma, R.S.
PAGES: 380 pages
PUBLISH DATE: 01/12/1996
ISBN Number: 1-55938-836-6
USA Book Price: $104.95
UK Book Price: £69.95
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